In The Non-Cotton Sock

A couple months ago I complained to the owner of my local running store that I was developing multiple blisters on the bottom of my feet ("battle wounds"). Normally I wouldn't care but I become a bit agitated when I have to end my run early because the pain is so bad. I was surprised when he didn't ask how old my shoes were or where I was running but the kind of socks I was wearing. To which I responded with your average bulk pack of ankle cotton socks from Costco. Immediately he told me "Cotton's Rotten. Go pick out some new ones on the wall and then we will talk about shoes." 
Yikes, I felt naive. So simple but something I completely overlooked.

I'd be lying if I said my blister went away for good. BUT I can say they are not caused by my socks, rather when I am wearing a new pair of shoes for the first couple times.

 I haven't tried enough brands to tell you which ones are best but the first brand I did buy (and have stuck with) have been wonderful. These are the SofSole Socks Coolmax Performance socks and you should be able to find these at your local sporting goods store. Other popular brands include PowerSox and Softwick which categorizes their socks by sport.

If you still aren't sure what is for you, as a general rule I recommend going with a sock that is around 50% polyester and higher is better. You want your foot to be able to breath in the sock but at the same time isn't falling down to the bottom of your shoe while working out. Therefore, try to find one described as a lightweight compression sock. Test some out and see what is right for you, I guarantee you feel the difference.